Accutane: Adverse Side Effects
ADVERSE SIDE EFFECTS: Urinary System: glomerulonephritis, nonspecific urogenital findings.
The kidney is thought to be damaged by exposure to the toxins that are excreted into the urine.
Acute glomerulonephritis is an inflammation of the glomeruli, bundles of tiny vessels inside the kidneys. The damaged glomeruli cannot effectively filter waste products and excess water from the bloodstream to make urine. Chronic glomerulonephritis can develop over a period of 10-20 years and is most often associated with other systemic diseases, including diabetes, malaria, hepatitis, or systemic lupus erythematosus. The kidneys appear enlarged, fatty, and congested
Mild glomerulonephritis may produce no symptoms, and diagnosis is made with laboratory studies of the urine and blood. Individuals with more severe cases of the disease may exhibit:
The individual with chronic glomerulonephritis may
discovery their condition with a routine physical exam
revealing high blood pressure, or an eye exam showing
vascular or hemorrhagic changes. The kidneys may be
reduced to as little as one-fifth their normal size,
consisting largely of fibrous tissues.
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