Fosamax Attorneys
Fosamax (Alendronate), manufactured by Merck, is indicated for the treatment and prevention of osteoporosis
(thinning of the bones) in men and women and for Paget's disease. Fosamax
is a type of drug known as bisphosphonates.
Recent studies are suggesting a connection between Fosamax and other bisphosphonates
and a serious bone disease called Osteonecrosis of the Jaw (ONJ), also
known as "Jaw Death" or "Dead Jaw". This condition
is associated with the interference of the blood supply to the bone. The
bone tissue in the jaw fails to heal after minor trauma such as a tooth
extraction, causing the bone to be exposed.
Osteonecrosis of the jaw can be extremely painful and may lead to additional
complications, such as infection, breakdown of the jawbone, and ulcerations
in the lining of the mouth. The exposure can eventually lead to infection
and fracture and may require long-term antibiotic therapy or surgery to
remove the dying bone tissue. It is not known if ceasing the use of Fosamax
can lower the risk of osteonecrosis of the jaw, as the bisphosphonate
medications metabolize slowly and remain in the bones for many years.
This study's finding was published in the Journal of Oral and Maxillofacial
Surgeons, and it prompted the US Food and Drug Administration (FDA) and
the manufacturer of Fosamax to issue a warning to health care professionals. The
FDA review concluded that all bisphosphonate
labels should mention osteonecrosis.
There have been many cases of ONJ in patients treated with
an oral bisphosphonate. Robert Marx, chairman of the division of oral
and maxillofacial surgery at Florida's University of Miami, says he's
aware of at least 40 or 50 cases of ONJ nationwide in patients who had
taken Fosamax.
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